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module menu icon Norethisterone: Mode of action

Norethisterone can be used to temporarily postpone a period but how does it work?

  • Norethisterone is a synthetic progestogen similar to the hormone progesterone.
  • When taken it acts in a similar way to the body’s own progesterone, by maintaining the uterine lining preventing it from being shed and therefore preventing the bleeding associated with a period.
  • It will continue to maintain this lining until cessation of the drug. 
  • A period (menstruation) should occur within three days of stopping the norethisterone. 

To temporarily delay a period - norethisterone is normally prescribed as a 5mg tablet, ONE to be taken THREE times a day, starting three days before expected menstruation.

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