Every traveller who requests advice will have a travel itinerary; sometimes this will be a single destination such as Dominican Republic whilst other times it will be a complex list of specific destinations. Identifying the traveller's chosen destination will enable you to confirm the specific disease risks and their distribution within the country.

When discussing a traveller's itinerary it is important to consider not only the final destination but also any stop over points as the patient will be exposed to differing levels of risk at each stage of their travel.

The risk of malaria can vary between regions within a country. Local control measures may have eliminated the risk within the towns whilst there is still a significant risk to travellers who venture to more rural areas.

Accommodation within urban areas is more likely to have better methods of screening at the windows or doors, and may also be air-conditioned. Urban transmission of disease is possible. There are areas where the Aedes mosquito transmits yellow fever or dengue fever because it has adapted to breed in standing water that is found within towns or cities in discarded cans or other containers.