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module menu icon The Adaptive Immune System

Immunity develops either naturally by infection with a foreign antigen, or artificially by vaccination.

On initial exposure to the foreign antigen, the production of antibodies develops over several days. On a 2nd exposure to the same antigen, the response is quicker as memory cells respond rapidly to produce the antibodies.  

Adaptive immunity is provided by T and B cells:

  • T-Cells (cell mediated immunity)
    • Activated by the antigen presenting cells
    • Differentiate into
      • T-Helper cells –  activates B-cells
      • T-Cytotoxic cells – Bind to and kill the foreign cells with the specific antigen
      • T-Suppressor cells –  Deactivate the cells once the goal has been achieved
      • T-Memory cells  - Remain in the body to react quickly on 2nd exposure to the antigen
  • B-Cells (humoral immunity)
    • Initial activation by T-Helper cells
      • Produce antibodies to specific antigen
    • Continual differentiation  of B-Cells into either
      • Memory cells (long lived)
      • Plasma cells (short lived)

Passive Immunity: This can be provided by the introduction of ‘ready made’ antibodies e.g.  antibodies crossing the placenta to protect a new born body. This protection is immediate but only short-term.  It doesn’t activate the immune response to produce an immunological memory.

 

For further information on Adaptive immunity you can watch the below videos:

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