The most effective way to treat rhinitis is by avoiding the allergen, but it can be difficult to avoid anything carried in the air we breathe. However, there are a number of self-help tips you can provide to patients to reduce their exposure.
Dust mites – damp dust weekly to remove the allergens, ventilate the house adequately, wash bedding weekly on a hot wash (60oC), use allergy proof bedding, use a vacuum cleaner that contains a high efficiency particulate air filter (HEPA) which removes more dust than a regular vacuum. If reactions are severe then carpet may need to be replaced with wood or vinyl floor coverings.
Pets – keep pets outside or limit them to one room, wash pets at least once a week.
Fungal moulds and spores – keep windows closed to prevent spores entering the house, use a dehumidifier to reduce moisture in the air, regularly inspect high risk areas for fungal growth. Keep bathrooms, kitchens and window frames clean, ventilate well to avoid damp, and avoid steam moving through the house when cooking or bathing by keeping kitchen or bathroom doors closed.
There is extensive advice that you can provide to patients who suffer from symptoms triggered by pollen:
• Wear wraparound sunglasses when outdoors to help stop pollen from getting in the eyes.
• Stay indoors when the pollen count is high (above 50).
• Keep windows (including car windows) and doors closed as much as possible.
• After being outdoors change clothes and take a shower to remove pollen from the body.
• Avoid cutting grass or reduce exposure to grassy areas.
• Vacuum and damp dust regularly as this will stop pollen from spreading around the house.
• Keep pets out of the house as the pollen can be transferred from their fur. If they do enter the house wash them regularly.
• Avoid drying clothes outside as pollen may stick to the washing and be brought in to the house.
• Avoid cigarette smoke as breathing in smoke can make hayfever symptoms worse as it irritates the airways, nose, eyes and throat.
• Rub a small amount of a pollen barrier product available as a balm or gel or petroleum jelly inside the lower nostrils as this can stop pollen from entering the nasal passages.
• Have a shower and wash hair after spending time outdoors.
Treatment
The first line of treatment should be OTC medication but if they fail to improve the symptoms then a patient may require prescription only medication.
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Numark Non-Drowsy Allergy Relief Tablets can be recommended to relieve the symptoms of hayfever and other
allergies e.g. pet or house dust mite allergies. They can also be recommended for skin allergies such as rash, itching and hives. Numark Non-Drowsy Allergy Relief Tablets contain 10mg of loratadine.
Dosage: Adults and children 2 years of age and weighing more than 30kg.
Antihistamines – work by blocking the effects of the chemical histamine which is released in response to an allergen when the immune system feels it is under attack by the allergen, in this case pollen. By blocking histamine they help relieve the symptoms of hayfever. Antihistamines help to treat the following symptoms but they may not unblock the nasal passages:
• itching
• sneezing
• watery eyes
• runny nose
Antihistamines are available OTC in various forms: tablets, liquids, eye-drops and nasal sprays. They can all be used in two ways:
• As and when – taken when the symptoms first appear.
• Preventative – is considered the better option and customers should be encouraged to continue taking the treatment throughout the hayfever season.
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Numark Antihistamine
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Numark Antihistamine 2mg/5ml Oral Solution can be recommended for the fast and effective relief from the itchiness, redness and swelling caused by skin allergies and hayfever. It also offers fast relief from nettle rash, heat rash, dermatitis, insect bites and reactions to food.
This solution contains 2mg of chlorphenamine maleate and is strawberry flavour.
Dosage: Adults and children over 1 year old.
Some people are wary of taking antihistamines such as chlorphenamine as these can cause drowsiness, however there are also formulations available that are non-drowsy for example loratadine. OTC antihistamine treatments contain one of the following ingredients:
• Cetirizine – Piriteze Allergy Tablets/Syrup, Benadryl One A Day Relief, Zirtek Allergy
Relief tablets, Numark Hayfever and Allergy Relief Tablets.
• Chlorphenamine – Piriton Allergy tablets, Piriton Syrup, Numark Antihistamine Tablets/Solution.
• Promethazine – Phenergan Tablets, Phenergan Elixir Oral Solution.
• Loratadine – Clarityn Allergy 10mg Tablets, Numark Non-Drowsy Hayfever and Allergy Relief Tablets.
• Acrivastine – Benadryl Allergy Relief.
* The above list is not exhaustive.
Corticosteroids such as beclomethasone (Beconase Hayfever Nasal Spray and Numark Hayfever Relief Nasal Spray) and fluticasone (Pirinase Hayfever 0.05% Nasal Spray) are available as nasal sprays to reduce nasal inflammation and irritation associated with hayfever. They are used as preventers – meaning they should be used twice a day (beclomethasone) or daily (fluticasone) throughout the hayfever season in order to prevent symptoms occurring. These nasal sprays need to be used for a few days before they control symptoms so it is often helpful to also use a decongestant nasal spray or a antihistamine during the first week or two.
Corticosteroid nasal sprays can only be sold for use in adults 18 years and over. They should not be used for more than 3 months at a time, and if they have shown no benefit in 7 days (fluticasone) or 14 days (beclomethasone) then the patient should be referred to their GP.
Eye drops containing antihistamine e.g. Otrivine Antistin are available over the counter and help to relieve the hayfever symptoms that affect the eyes such as inflammation, redness, itchiness and watering. These drops relieve symptoms quickly but should not be used for more than seven days. Patients should be warned that they can sting when first used but this discomfort should disappear once the patient has blinked a few times.
The most commonly used eye drops, Optrex Allergy Eye Drops, Numark Hayfever 2% Eye Drops and Opticrom Allergy eye drops, contain the active ingredient sodium cromoglicate which prevents the release of histamine from mast cells in the airways and mucous membranes. It is very effective at both treating and preventing hayfever symptoms from occurring if used continuously – the drops should be used every day even if the person doesn’t have symptoms.
It is important to ensure patients use the correct technique when applying eye drops because if they are not then they will not benefit from the treatment. Refer patients to the PIL and explain how to administer the drops correctly or refer to the pharmacist.
Featured product
Pirinase Hayfever 0.05% Nasal Spray
Pirinase Hayfever Nasal Spray – formerly known as Flixonase – is more effective than antihistamine tablets at relieving the nasal symptoms of hayfever1-5 and despite being a nasal spray, treats more than just nasal symptoms, including itchy and watery eyes,6 offering complete hayfever relief.
Used daily, it can prevent airborne allergy symptoms from developing, and so prevents and protects against
hayfever. To find out more about this and how to recommend Pirinase Hayfever Nasal Spray, visit www.mypharmassist.co.uk and register for the Allergy Training in the Training Resources section.
1. LaForce C. J Allergy & Clin Immunol. 1999; 103: S388-94.
2. Brozek JL et al. J Allergy & Clin Immunol, 2010; 126 (3): 466-476.
3. Van Cauwenberge P et al. Consensus statement on the treatment of allergic rhinitis.
Allergy, 2000; 55: 116-134. 7. Dykewicz MS et al. Ann Allergy Asthma Immunol. 1998; 81:
478-518.
4. Yanez A and Rodrigo G. Ann Allergy Asthma Immunol, 2002; 89: 479-484.
5. Nielsen LP, Dahl R.. Am J Respir Med. 2003; 2 (1): 55-65.
6. Bernstein DI et al. Clin Exp Allergy. 2004; 34: 952-957. 7. Howarth PH. Allergy. 2000; 55
Suppl 62: 6-11. 8. Rak S et al. Clin Exp Allergy. 1994; 24: 930-939.
Pirinase Hayfever 0.05% Nasal Spray Product Information. Presentation: Aqueous nasal spray suspension containing 50 micrograms of fluticasone propionate per spray. Uses: Prevention and treatment of allergic rhinitis.
Dosage and administration: Intranasal use only. Adults and the healthy elderly: Two sprays into each nostril once a day, preferably in the morning. Use twice daily if required. Do not use more than 4 sprays a day in each nostril. Prophylaxis of allergic rhinitis requires treatment before contact with allergen. Children under 18 years: Not to be used. Contraindications: Known hypersensitivity to ingredients. Precautions: If symptoms have not improved after 7 days or, if symptoms have improved but are not adequately controlled, consult a doctor. Not to be used for more than 3 months continuously without consulting a doctor. Consult a doctor before use in: concomitant use of other corticosteroid products, fever, nasal/sinus infection, recent nasal injury/surgery, nasal ulceration. Infections of nasal airways should be appropriately treated. Care must be taken when withdrawing patients from systemic steroid treatment, and commencing therapy with intranasal fluticasone propionate, particularly if there is any reason to suspect impairment of adrenal function. Risk of adrenal suppression with higher than recommended doses. Significant interactions between fluticasone propionate and potent inhibitors of the cytochrome P450 3A4 system, e.g. ketoconazole and protease inhibitors, such as ritonavir, may occur. This may result in increased systemic
exposure to fluticasone propionate. Systemic effects of nasal corticosteroids may occur, particularly at high doses prescribed for prolonged periods. Side effects: Dryness and irritation of the nose and throat, unpleasant taste and smell, headache and epistaxis. Hypersensitivity reactions including skin rash and oedema of the face or tongue. Rarely anaphylaxis/anaphylactic reactions and bronchospasm. Very rarely glaucoma, raised intraocular pressure and cataract. Extremely rarely nasal ulceration and nasal septal perforation usually following previous nasal surgery. Pregnancy and lactation: Do not use except with medical advice. Overdose: Administration of doses higher than those recommended over a long period of time may lead to temporary suppression of adrenal function. Legal category: P. Product licence number: PL 00079/0616. Product licence holder: GlaxoSmithKline Consumer Healthcare, Brentford, TW8 9GS, U.K. Package quantity and RSP (excl. VAT): 60 spray pack £5.95. Date of last revision: October 2012. PIRINASE and the Trigger device are registered trademarks of the GSK group of companies
Nasal decongestants can be used to relieve a blocked nose as they reduce swelling of the blood vessels and open the nasal passage to help with breathing. Some antihistamines include decongestants to help relieve nasal symptoms. If patients choose a product that does not contain antihistamine then it will only unblock their nose. Ensure that when you are recommending a product that you advise patients of the differences.
Topical decongestants (nasal drops or sprays) can be a short-term treatment for the nasal symptoms of hayfever. They should only be used for a maximum of seven days as they can cause rebound congestion (the symptoms of congestion worsen). They can also cause dryness and irritation in the nasal passage.
If OTC and prescribed treatments do not work then patients can be referred for immunotherapy treatment which exposes the sufferer to the allergen gradually increasing the doses to “train” the immune system to not overact. This helps to reduce the sensitivity to the allergen and can be administered by tablets or injection.